severe combined immunodeficiency disease

Definitions of severe combined immunodeficiency disease

1. noun

   a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
   synonyms: SCID, severe combined immunodeficiency

   types:

   ADA-SCID

   SCID resulting from mutation of a gene that codes for adenosine deaminase

   X-SCID, X-linked SCID

   SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor

   type of:

   immunodeficiency

   immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced

   monogenic disease, monogenic disorder

   an inherited disease controlled by a single pair of genes